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C F S
- Information International Ampligen
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What is Ampligen ?
Ampligen is an artificial RNA (ribo-nucleic-acid),
an RNA which has been "wrongly" cross bound. The manufacturer
of Ampligen is the Peer Reviewed Research Papers: Close to zero
Normally one would expect a
constant stream of scientific literature when a new and efficient drug is
being introduced. On Ampligen, however, the mode of action in clinical
studies, its effects and side-effects etc., is not yet available. Four
1994-abstracts,
Suhadolnik et al., 1994. Mechanism of action of Ampligen ?
The exact mechanism of action
of Ampligen in humans is still largely unknown. It is believed that
Ampligen interacts with both viruses and the body's acute phase
response: Kimura-Takeuchi et al., 1992, Hendrix et al., 1993, Kimura et al., 1994, and Majde et al., 1998. Preliminary results
At the 1999-CFS conference,
Ampligen was presented as being beneficial to severely ill patients, news, Demeirleir et al., 1999. At the 2001- AACFS conf., Hemispherx
presented the first results of the so-called 511-study, Ampligen, my own comments, 2001. A study
involving 2 (two) women with impressive results, Snell et al., 2001. At the 17th International Conf.
on Antiviral Research in 2004, Hemispherx Biopharma, the makers of Ampligen,
finally presented a paper by Carter et al.
Their results included 234 patients from 12 centers involved in the
phase III study, ampligen04.txt. Review of Department of Health and Human Services CFS
Advisory Committee Fifth meeting in Final approval 2008 ?
CEO of
Hemispherx announced that he expects the application be completed in early 07,
ampligen.drug.filing07.txt, but
final application is filed in Oct. 07, hemispherx.new.drug.application07.txt.
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