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Central  Sensitivity  Syndromes

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Central Sensitivity Syndromes

Is FM a disease of the brain ?,schweinhardt.etal07.txt.

 

Central sensitization: a biopsychosocial explanation for chronic widespread pain in patients with fibromyalgia and CFS, meeus.nijs06.txt. Psychophysical and neurochemical abnormalities of pain processing in FM, staud.spaeth08.txt.

 

Comorbid somatic symptoms and functional status in patients with fibromyalgia and CFS: Sensory amplification as a common mechanism, geisser.etal08.txt. Functional incapacity and physical and psychological symptoms: How

they interconnect in CFS, priebe.etal08.txt, priebe.etal.08.txt, priebe.etal08.pdf.

 

Central nervous system abnormalities in fibromyalgia and CFS, gur.oktayoglu08.txt.

 

The unifying concept of Central Sensitivity Syndromes, yunus07.txt.  A new paradigm and group nosology for  fibromyalgia and overlapping conditions, and the related issue of disease versus illness, yunus08.txt.

 

 

Research explaining the increased sensivity:

Increased glutamate in cerebrospinal fluid, peres.etal04.txt.

Altered intestinal permeability in patients with FM, goebel.etal08.txt.

 

Stress induces a switch of intracellular signaling in sensory neurons in a model of generalized pain (rats),  khasar.etal08.txt. Visceral sensory neurons that innervate both uterus and colon (rats), chaban08.txt.

 




 
 

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Mette Marie Andersen, MD