Journal of Chronic Fatgigue Syndrome Volume 13, Number 4, 2006 Conservation of Resources and Quality of Life in Individuals with Chronic Fatigue Syndrome Renée R. Taylor, Supriya Kulkarni, Yukiko Shiraishi. Objective: To examine the relationship between resources and quality of life in individuals with chronic fatigue syndrome (CFS). Participants and Study Design: A cross-sectional design was used to describe associations between resource loss and gain and quality of life for 47 individuals diagnosed with CFS. Main Outcome Measures: The Conservation of Resources Evaluation was used to measure resources in terms of perceived loss and gain. Health-related quality of life was assessed with the Quality of Life Index. Results: Total resource loss and total resource gain were significant correlates of overall quality of life. Gains in self-esteem, energy, and work resources were associated with higher-perceived quality of life. Material loss and energy loss were associated with lower-perceived quality of life. Conclusions: Findings for the relationships between perceived resources of self-esteem, work, material items, and energy and perceived quality of life can be used inform future rehabilitation efforts. These relationships appear to occur independently of illness severity among individuals CFS. KEYWORDS. Conservation of resources theory, quality of life, chronic fatigue syndrome.