Chronic fatigue syndrome and sexual dysfunction Journal of Psychosomatic Research, Volume 56, Issue 2 , February 2004, Pages 199-201 Ruud C. W. Vermeulen [a, *] and Hans R. Scholte [b] Affiliations: [a] CFS Research Centre Amsterdam, Waalstraat 25-31, 1078 BR, Amsterdam, The Netherlands [b] Department of Biochemistry, Erasmus MC-University Medical Centre Rotterdam, Rotterdam, The Netherlands [*] Corresponding author. Tel.: +31-20-4706290; fax: +31-20-4706299 E-Mail: mailto:rcwvermeulen@cfscentrumamsterdam.nl Received 3 March 2003; accepted 11 June 2003. Available online 4 March 2004. Abstract Objective: The study was undertaken to determine if ambulant female patients with the chronic fatigue syndrome (CFS) report problems with their sexual functioning. Methods: We studied 35 female CFS patients and 36 healthy female controls. The severity of CFS was measured with a fatigue questionnaire and the presence and severity of sexual dysfunction with a questionnaire about sexual functioning. Results: The mean fatigue score was 24.8 in the CFS patients and 11.9 in the controls (P=.000). No increase in sexual dysfunction was found in the CFS group. The control group showed negative correlations between the score of the fatigue questionnaire and the frequency of "sexual fantasies," "(desire for) sexual contact" and "satisfaction with sex life." Such correlations were absent in the CFS group. Conclusion: The satisfaction with sex life was similar in patients and controls. The results suggest that patients and controls have a different perception of fatigue. Author Keywords: Chronic fatigue syndrome; Depression; Sex life; Sexual functioning Copyright © 2004 Elsevier Inc. All rights reserved.