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Inflammation  / Brain  Inflammation

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The Inflammatory Response

The inflammatory response is by nature designed as the body's means of coping with various traumas and infections.   However, overreaction of the inflammatory response has proven very harmful to the body. A perfect example of the harmful effects of inflammation is the destruction of joint tissue in Rheumatoid Arthritis:  NEJM, Mar 22, 2001. 

 

Likely explanation for all pain: Inflammation, omoigui07.txt. 

 

Identification and treatment of symptoms associated with inflammation in medically ill patients, dantzer.etal07.txt, dantzer.etal07.pdf.
 

 

Studies on Inflammation in CFS and FM

Decreased DHEA sulfate but normal insulin-like growth factor in CFS: Relevance for the inflammatory response in CFS, maes.etal05.txt. Low grade inflammation and arterial wave reflection in patients with CFS, spence.etal07.txt.

A subset of FM patients have findings suggestive of chronic inflammatory demyelinating polyneuropathy and appear to respond to IVIgIn FM, caro.etal07.txt.

 

Lymphocyte Glucocorticoid Sensitivity

Glucocorticoid sensitivity of immune cells in severely fatigued adolescent girls: A longitudinal study, wolbeek.etal.07.txt, wolbeek.etal07.txt, wolbeek.etal07.pdf.  HPA axis reactivity and lymphocyte glucocorticoid sensitivity in FM and chronic pelvic pain, wingenfeld.etal07.txt.

 

The Brain

More and more evidence has been pointing in the direction of CFS being caused by inflammation in the brain, klimas06.txt.

A study on the effect of cytokines on brain functioning was referred in the press,  Yirmiya et al., 2001.

On psychological stress including the influence of sex hormones:  Maes et al., 1999  and   Song et al., 1999.

On posttraumatic stress disorder (PTSD):  Maes et al., 1999.

 

The Brain in FM

A study in FM patients on the relations between neural and immune functions in the brain,  Lekander et al., 2000. 

Psychopharmacological medicine, including antidepressive medicine influence the brain inflammatory response,  Maes et al., 1999.
 


 
 

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Mette Marie Andersen, MD