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C F S
- Information International Sleep and CFS/
FM
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Sleep
Mechanisms
of immune-to-brain and brain-to-immune signaling involved in mediating
physiological sleep and altered sleep with disease, lorton.etal07.txt, lorton.etal07.pdf. Sleep
characteristics of persons with CFS and non-fatigued controls: reeves.etal.06.txt, reeves.etal06.txt. Evidence for the existence of objective
alpha-delta sleep disturbances in CFS, vanhoof.etal.07.txt,
vanhoof.etal07.txt, vanhoof.etal07.pdf. Twin studies have demonstrated differences
in reaction to sleep delay, armitage.etal07.txt,
armitage.etal07.pdf. Periodic breathing during sleep is affected in
FM, shah.etal06.txt. Disturbed alpha-sleep in FM, Roizenblatt et al., 2001.
Hypersomnolence in FM patients and polysomnographic abnormalities
correspondingly, Sarzi-Puttini et al., 2002. Actigraphy useful for
monitoring sleep patterns in FM and depression, Korzun et al., 2002. The alpha
wave sleep pattern characteristic of FM is the same as in primary sleep
disorder, Schneider-Helmert et al., 2001. Cyclic patters of symptoms are
characteristics for FM, including the cyclic nature of sleep problems, rizzi.etal04.txt. Good-quality sleep acts as a biobehavioral resource
that minimizes allostatic load, hamilton.etal07.txt Most CFS patients report sleeping problems, but
studies have not revealed a CFS-specific
pathological pattern, Le
Bon et al., 2000, pdf. More recently, however, the same researchers found paradoxical Nrems distribution
in "pure" CFS, le.Bon.etal07.txt, le.Bon.etal07.pdf. Sleep impairment and
depressive symptoms in CFS are independent, Graffelman et al., 2002. CFS sample had a
very high incidence (58%) of undiagnosed primary sleep disorder such as sleep
apnea/hypopnea syndrome and restless legs/periodic limb movement disorder, fossey.etal04.txt. Sleep quality perception in the CFS: Correlations with sleep
efficiency, affective symptoms and intensity of fatigue, neu.etal.07.txt, neu.etal07.txt,
neu.etal07.pdf. Discordant twins had different sleep patterns but
CFS symptoms did not correspond to sleep pattern, Watson et al., 2003. Also in a futher study, the Cerebrospinal Fluid
Normal cerebrospinal fluid levels of hypocretin-1 (orexin A) in patients
with FM, taiwo.etal07.txt. Circadian Rhythms
A study of body core
temperature found no different circadian rhythm in CFS compared to
normal, Hamilos et al., 2001. Continuous waist activity measurements
disclosed lower activity in the day, but increased at night, tryon.etal04.txt.
Regulation of circadian rhythm by use of medication (melatonin) or
phototherapy does not improve symptoms of CFS, nijs.on.waterhouse03.txt. Sleep Studies
Basic knowledge on sleep-wake
patterns are still scarce, one study focuses on the neuroimmune regulation of
sleep, Rogers et al., 2001. Prevalence of nonrestorative
sleep complaints in the general population, ohayon05.txt,
ohayon05.pdf. Sleep quality in patients with FM
using the Pittsburgh Sleep Quality Index, osorio.etal06.txt. Studying for sleep disturbance, a first night effect
is to be taken into consideration before clinically significant habituation, lebon.etal03.pdf.
A recent study on SAQ(c) sleep factors found indications of
significant abnormalities with CFS, unger.etal04.txt,
unger.etal.04.txt. Women with FM had fewer mean spindles per
minute of NREM stage 2 sleep and lower mean spindle
time per epoch of NREM stage 2 sleep, landis.etal04.txt. Sleep Medication
The drug Modafinil has helped
one (1) individual with CFS to recover, turkington.etal04.txt,
turkington.etal04.pdf. A meta-analysis of FM and sleep
medication cyclobenzaprine, tofferi.etal04.txt. |
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