Date sent:      	Fri, 14 Sep 2001 1

The CFIDS Association of America sent the following letter to the King's
College WHO Collaborating Centre today. It is virtually identical to the
letter sent to Dr. Brundtland of WHO on Septmber 5th, with minor
modification to the second paragraph.

Vicki Walker
The CFIDS Association of America


September 14, 2001


Professor Rachel Jenkins
WHO Collaborating Centre
Institute of Psychiatry
De Crespigny Park
London SE5 8AF

Via e-mail: r.jenkins@iop.kcl.ac.uk

Dear Prof. Jenkins:

The CFIDS Association of America, Inc., has recently learned of a booklet
titled WHO Guide to Mental Health in Primary Care, developed by your World
Health Organization's Collaborating Centre for Research and Training for
Mental Health at the Institute of Psychiatry, Kings College, London, and
published in book form and on the Internet at
http://www.whoguidemhpcuk.org/.

The CFIDS Association joins with Action for ME, IMEGA-e, the ME Association,
and other international CFS/ME organizations in taking grave exception to
the section of this booklet on chronic fatigue syndrome (CFS), as the
information is inconsistent with current research on CFS as well as with WHO
's own International Classification of Diseases, 10th revision.

The ICD-10 index codes "chronic fatigue syndrome" at G93.3 in the chapter on
the nervous system and the category "other diseases of the brain." However,
the Kings College booklet lists CFS at F48.0 in the category "neurasthenia,"
a designation which specifically excludes code G93.3 illnesses.

The diagnostic criteria for CFS in the booklet are not consistent with the
internationally accepted criteria published in the Annals of Internal
Medicine in 1994. Rather, they reflect relatively loose criteria used only
by a small number of researchers and clinicians in the U.K. It is surprising
that the 1994 international criteria would not be provided, given that Dr.
Simon Wessely, an author of the CFS section of the WHO Guide, is also an
author on the 1994 international definition, and the looser criteria predate
the international definition, which is considered to replace earlier
definitions.

CFS is not considered by leading researchers of the illness to be a mental
disorder, as indicated by the WHO Guide. Numerous biological abnormalities
of the immune, endocrine and circulatory systems have been documented,
although the etiology of CFS is not yet known. These abnormalities are not
described or referenced in the WHO Guide. Risk and perpetuating factors
noted in the accompanying article on CFS at
http://cebmh.warne.ox.ac.uk/cebmh/whoguidemhpcuk/leaflets/06-2.html have
never been proven to be associated with CFS. In fact, the cause(s),
precipitant(s) and perpetuator(s) of CFS are not yet known, therefore the
WHO Guide contains misleading information when it states that lifestyle
factors are responsible for the development of CFS.

Because the information on chronic fatigue syndrome in the WHO Guide to
Mental Disorders in Primary Care is inaccurate, incomplete and inconsistent
with WHO's own guidance in the ICD-10, The CFIDS Association of America
calls for the immediate removal of this section from the booklet.

It also appears that WHO has departed from the common requirement of a
disclaimer for this booklet, such as the one used in a WHO publication on
substance abuse
(http://www.who.int/substance_abuse/PDFfiles/needsassessment.pdf):

"This document is not a formal publication of the World Health Organization
(WHO) and all rights are reserved by the Organization. The views expressed
in documents by named authors are solely the responsibility of those
authors."

Please find attached a CFS Fact Sheet outlining current CFS research
findings, most of which are overlooked by the King's College booklet
authors. The CFIDS Association of America would be pleased to provide
additional supporting documentation to WHO as it addresses this complaint.
If you require additional information, please contact me by fax at
704-365-9755, e-mail at kkenney@cfids.org or telephone at 704-364-0466.

Sincerely yours,



K. Kimberly Kenney
President & CEO

cc:       Dr J.M. Bertolote, Mental Behavioural Disorders, WHO,
bertolotej@who.ch
             Ms. Jo Paton, Research Worker, WHO Collaborating Centre,
j.paton@iop.kcl.ac.uk
             Dr. Ellen Goudsmit, IMEGA-e, ellengoudsmit@hotmail.com